Sentence examples for novel subclass from inspiring English sources

To enable the specific and efficient isolation of VHH genes from peripheral blood B-cells, the long and short-hinge sequences of Lama glama heavy chain IgGs were determined, revealing the presence of a novel subclass of short-hinge heavy chain IgG.

We named the protein ClpK as it constitutes a separate subclass within the Clp ATPase family and K. pneumoniae ClpK is the prototype of this novel subclass.

More recently, evidence has accumulated that the EML4-ALK fusion gene defines a novel subclass of lung adenocarcinomas with distinct clinicopathological features [ 7- 9], so that it has emerged as a target for therapy.

We have identified the existence in several mammalian species of a gene encoding a putative four-transmembrane protein, BCMP1, wich defines a novel subclass in this family of proteins.

These pronounced differences between sAC-HD and other known haem sensor domains might indicate that sAC-HD represents a novel haem protein class, possibly a novel subclass within the H-NOX family [ 30].

Similarity searches in protein domain databases identified partial sequence conservations with peripheral myelin protein 22 (PMP22)/ epithelial membrane proteins (EMPs) and Claudins, defining the encoded protein as representative of the existence of a novel subclass in this protein family.

The purpose of this paper is to introduce two novel subclasses and of meromorphic valent functions by using the linear operator.

This facilitates a better discovery of novel subclasses within the same developmental stage.

In this respect, AdoMetDC from T. brucei and other trypanosomatids represent a novel structural subclass of eukaryotic AdoMetDCs, that otherwise exist as monomers (e.g. plant AdoMetDC) or homodimers (e.g. mammalian AdoMetDC) [ 8].

The most recent large-scale study combining DNA copy number changes with gene expression profiles (METABRIC) led to the identification of 10 novel "integrative" subclasses with a different prognosis according to subclass [ 4].

In contrast, >1000 genes were differentially expressed in primary tumors progressing to liver metastases, thus identifying a novel breast cancer subclass comprising ~15% of our cases.