Because certain dermal collagen AGEs, such as pentosidine and cross-lines, contain fluorescent cross-links (10), skin intrinsic fluorescence (SIF) can be quantified and act as a novel maker of AGE accumulation.
Both COL2A1 and ACAN gene expressions were significantly upregulated with all growth factors, whereas novel maker gene expression was significantly upregulated after GDF6 stimulation, in particular in AD-MSCs.
In his brilliant new novel Makers, Cory Doctorow, a firebrand left-wing blogger, social critic and sci-fi novelist, paints a vivid and compelling portrait of a near future that feels an awful lot like the present.
(Although the trope is popularly named after astrophysicist Freeman Dyson's 1960 paper, others have traced it back to Olaf Stapledon's 1937 novel, Star Maker).
The Yapp beta has been used for conferences, weddings, romance novel bookclubs, maker faires, youth ministry gatherings.
He was inspired by the mention of the concept in the 1937 science fiction novel Star Maker, by Olaf Stapledon, and possibly by the works of J. D. Bernal, Raymond Z. Gallun, and Edgar Rice Burroughs who seem to have explored similar concepts in their work.
Just like ER regulating PR pathway, and both of them making the most important molecular markers of breast cancer, RNPC1 could develop to a novel molecular maker as a downstream factor of p53.
To ensure scalability and computational tractability, a novel price-maker day-ahead bidding algorithm is proposed, which is formulated in terms of simple energy requirement constraints.
Interestingly, in NSCLC, poorly differentiated carcinomas are difficult to classify, and as such, the identification of novel prognostic makers for this particular group may help improve the therapeutic outcome of the patients.
But whereas, say, Richard Powers's most recent novel, "The Echo Maker," is explicitly about the phenomenology of this delusion, complete with a barrage of neurological facts, Galchen's novel more boldly denies us the comfort of a conclusive explanation.
For comparison, here is a man looking at his wife, in Richard Powers's earnest and unironic novel "The Echo Maker": "He held back a lock of her mocha hair and grazed her forehead.
