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The mechanism of frequency-decoding in the gonadotrope was further clarified by the novel elucidation of the role of ERK5 in FSHβ expression.
The high sensitivity of the nCounter assay allowed for novel elucidation of miRNAs that had been significantly altered by DE exposure.
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An exploration of common rules (property motifs) in amino acid sequences has been required for the design of novel sequences and elucidation of the interactions between molecules controlled by the structural or physical environment.
The elucidation of novel alkaloid biosynthetic and catabolic pathways wil continue to furnish new biocatalysts for the synthetic organic chemist.
Thus, compound 12 is a novel tool for the elucidation of the pharmacological relevance of 17β-HSD1 and might be a lead for the treatment of estrogen-dependent diseases.
This work presents the first quantification of the dynamics of cell mechanical reinforcement under stress, which is a novel insight into the elucidation of the more general phenomenon of cell adaptation to stress.
The ligand binding motif unraveled by 1,8-ANS may open new possibilities to treat TTR amyloid diseases by the elucidation of novel candidates for a more specific pharmacophoric pattern.
The paper presented a comprehensive theoretical and experimental study on the molecular drugs-design, synthesis, isolation, physical spectroscopic and mass spectrometric elucidation of novel functionalization derivatives of Cytisine (Cyt), using nucleosidic residues.
Identification of these receptors will be instrumental for elucidation of novel activities of extra-cellular sphingolipids, and may pave the way for the design of new sphingolipid mimics for the treatment of inflammatory diseases, and pathologies which depend on cell migration, as in metastatic tumors.
Such a fragment dereplication approach can assist with the elucidation of novel compounds with similar scaffolds to known compounds and thus reduce time spent on structure generation.
The zebrafish is a valuable vertebrate model system for the elucidation of novel molecular pathways of aging as well as early development [60].
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CEO of Professional Science Editing for Scientists @ prosciediting.com