Sentence examples for novel checkpoint from inspiring English sources

In the weeks before the Republican convention, Alfred A. Knopf, fresh from its merchandising triumph with Bill Clinton's "My Life," will release Nicholson Baker's incendiary vest-pocket-size novel, "Checkpoint," in which a politically ambidextrous protagonist (he hates both abortion and Dick Cheney) lays out a case for assassinating the president.

I think what's most offensive about Leon Wieseltier's scummy (to borrow his term), supercilious and gallingly fatuous+dismissal of Nicholson Baker's novel "Checkpoint" is that Wieseltier scoffs at the general idea that the Bush administration is a+radical one, the likes of which we have rarely, if ever, seen in this country.

Baker caused a stir in 2004 with his slim novel "Checkpoint," in which the protagonist wants to assassinate President Bush, and an outcry in 2008 with "Human Smoke," which gathered newspaper clippings, diary entries and other contemporary sources to make a pacifist case against World War II.

Furthermore, we have identified Net1 and RhoA as key molecules controlling the activation of this novel checkpoint pathway (Figures 7 and 8).

Taken together our data support BRCA1 playing a critical role in a novel checkpoint pathway that senses DNA damage within actively transcribed DNA to initiate cleavage and degradation of stalled RNAPII elongation complexes.

We have recently shown that GSCs with misoriented centrosomes do not enter mitosis until the orientation is corrected, pointing to the presence of a novel checkpoint that monitors centrosome orientation ("the centrosome orientation checkpoint") [21].

SAND is designed to operate under high-speed network traffic, and it uses a novel checkpointing protocol which can perform failure recovery based on upstream backup and checkpointing.

Various combination approaches using these novel checkpoints may yield a therapeutic edge in the battle against a range of cancers.

Ssa1 and Ssa2 are novel G2/M checkpoint proteins that copurify with the DNA damage-dependent checkpoint protein, Rad9, and function after ultraviolet light irradiation in phosphorylating Rad9 and another checkpoint protein, Rad53 (Gilbert et al. 2003).

Despite the promising data of novel immune checkpoint inhibitors, only a small subset of patients with UC achieves durable remissions.

Thus, nivolumab is a novel immune checkpoint inhibitor that exerts its anti-tumor effect by inducing PD-L1/PD-L2 binding and maintaining T cell function [11].