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When applied in vivo, the notion of "threshold hydrophobicity" would allow the selective incorporation of transmembrane segments into the lipid bilayer during the biosynthetic translocation process without the requirement of any additional expenditure of energy.
Cai et al. [12] considered a more general model that incorporates the notion of threshold strategy.
The notion of threshold is already an approximation which is not sharply defined in Hodgkin-Huxley [35] or Fitzhugh-Nagumo [40, 41] models (more precisely it is not a constant but it depends on the dynamical variables [55]).
Consistent with Asongu and De Moor (2017), the notion of threshold is in accordance with Cummins (2000) on the minimum level/threshold in language proficiency before rewards are acquired in a second language.
In such cases, the standard notion of threshold, as defined by the NOAEL concept, is not inclusive of all potentially harmful effects.
We used conceptual change theory, combined with the notion of threshold concept learning as a heuristic, to begin to examine the development of students' mental frameworks or cognitive structures and their understanding during this new integrated genetics unit.
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This supports the notion of threshold-dependent fate determination, as recently reported for the TF ETV2 in hemangiogenic fate specification50.
For the purposes of this review, we will use estrogens and interaction with the estrogen receptor as an example system by which to assess the notion of thresholds for endocrine disrupters.
The model is built on the notions of threshold and knowledge weight from the discipline of machine learning.
The likely development pathways of post-mining landscapes were identified by comparing the planned severity of the disturbance impact and associated rehabilitation design (according to Doley et al. 2012) to which the notions of threshold ir/reversibility have now been added to distinguish between the respective domains of near/natural, hybrid and novel ecosystems (according to Hallett et al. 2013).
The findings from the present study fit the notion of a threshold model that is, that there is a threshold at which chronic physical exposures begin to have effects on health outcomes, and that one role of chronic stress may be to lower the threshold at which physical exposures affect biologic and clinical outcomes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com