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Delayed cell surface internalization may actually provide an advantage by prolonging antigen presentation to augment CTL priming, a notion consistent with our previous observation that Δ7 mice consistently generated more vigorous antiviral CTL responses compared to KbWT mice [21].
Although phosphate and carbonate peaks were obtained consistently for serum granulations when subjected to the FTIR analysis, it is speculated that the absence of noticeable carbonate and phosphate peaks in some of the Raman spectra may be due to the overwhelming presence of proteins in the serum granulation samples, a notion consistent with published studies [45].
Thus, these results indicate that CD8 dependency is inversely correlated with the potency of the agonist ligand, a notion consistent with data reported in other studies 23.
First, with this hypothesis in mind, let us consider that huα-syn undergoes anterograde axonal transport from the OB in our paradigm (see Fig. 9), a notion consistent with the dual-hit hypothesis [ 31].
The authors hypothesize that there is an optimal concentration, specific to each mutated variant of TTR that determines the rate of toxic aggregate formation and consequently its effect on the phenotype, a notion consistent with earlier studies in cultured cells.
The relationship between reduced sMg levels and atrial fibrillation suggests that low sMg status may play a role in arrhythmogenesis, a notion consistent with previous research showing an association between hypomagnesemia and development of atrial fibrillation in the general population [ 21].
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This notion seems consistent with the notion of a special-self system.
This notion is consistent with the observed simultaneous increase of As, V, and Fe (Fig. 5).
This notion is consistent with the role of microtubules in transporting PODXL to the apical surface in polarized ECs.
Such a notion is consistent with prior work, including Allport's (1985) thesis, stating that distributed assemblies of neurons firing in distinctive patterns represent conceptual knowledge.
This notion is consistent with alpha activity reflecting functional inhibition.
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