In particular, while the depth of annotation considered here is sufficient to noticeably improve inference for association, it is clear from recent ENCODE Project Consortium publications that it reflects only a small fraction of the complexity present in the regulatory landscape.
Tumors formed by Ptgs1/Ptgs2 −/− BrafV600E cells were noticeably smaller than their COX-sufficient counterparts even before adaptive immunity is expected to impact on tumor size.
However, in real-world applications, it's noticeably time-consuming and unpractical to collect sufficient labeled training data for each task.
However, the most antifungal compound among the potential inhibitors, isothiazolo[5,4-b]quinoline, did not appear to affect the metabolism of brassilexin noticeably, suggesting that growth inhibition is not sufficient to slow down the rate of brassilexin detoxification.
It's best to make sure the pies bake until the filling is noticeably bubbling, ensuring that the thickener has had sufficient time to cook through and activate.
The concentration of these defects and thus the local disorder can be noticeably reduced through decreasing the |Vd| down to a sufficient low level.
Furthermore, even though total Dsh levels are significantly reduced when Dbo is overexpressed, this again does not noticeably affect Wnt signalling, suggesting that the remaining Dsh is sufficient for Wnt signalling activity.
The slightly coarser AUV bathymetry remained sufficient to derive terrain variables for the Acesta Wall, but point density was noticeably too sparse for the Coral Wall, resulting in no significant relationships.
Individually, mutations N175Q and N178Q did not noticeably alter the size of the protein, indicating that those residues by themselves are not sufficient for Btn1p glycosylation.
Neither of these predictors on their own could make a model that would have sufficient sensitivity and specificity; however, combining the prior odds of individual genes and SIFT score noticeably improved the predictive performance relative to either alone.
