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Although there was similarity of the classes over time, there was also noticeable variability in the thresholds of several indicators.
It must be stated, however, that heterozygous MMTV-Luc2 (MMTV-Luc2 het ) females presented noticeable variability in the strength and distribution of luminescent signal, as determined by non-invasive whole animal imaging (see below).
Although the mean height of the row of longest stereocilia was not significantly reduced at any age examined up to 4 months (Table 1), there was a noticeable variability in the length of the longest stereocilia within the bundles of individual IHCs, which became more apparent with age (compare Fig. 5B with Fig. 5D and E; see also Supplementary Material, Fig. S2).
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Looking at the concrete formation of the motifs contained in these two groups shows that the only noticeable variability lies in positions 1 and 3 of the motifs.
Despite noticeable inter-individual variability in the spleens of control mice, AChE protein level and enzymatic activity were very significantly lower (70%and96%6% decrease, respectively) in spleen from infected mice compared to control.
Other than disease severity it is also interesting to ask whether expansion size has an effect on perhaps the most noticeable source of variability in the C9ORF72 disease phenotypes: the primary group of neurons affected.
When reviewing the literature, it was noticeable that studies demonstrated variability in rates of HER2 overexpression (Table 3), making our results difficult to compare with other published series.
Additionally, the DMVCs presented a more noticeable trend of increased methylation variability in obesity cases compared with DVCs.
In particular, the panels chosen specifically because they were polymorphic in either the Bavarian or Norwegian populations alter the scatter of the data with respect to the whole data set panels (all 306 and random 104 SNPs), with the difference being most noticeable in the Norwegian data set, where the variability in Norway is dramatically inflated versus the other populations.
It is also of interest to note that the T1DM group demonstrated larger variability in echopattern (larger IQR) compared to the control group, particularly noticeable for echo type I and II at day-2 and day-4 post run.
Figure 6a demonstrates that for the two radiologists at least, there was a noticeable increase in the intraclass correlation coefficient between reads 2 and 3, showing that there was reduced variability in submitted confidence scores.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com