Sentence examples for noticeable toxicity from inspiring English sources

In particular, 4,6-dimethoxy-4′-ethylazaaurone 22 showed antiplasmodial potency without noticeable toxicity.

The most noticeable toxicity arises from DNA destruction in mouse embryonic stem cells (mESCs), due to the increased oxidative stress.

An MTT assay was performed to check cytotoxicity of Au NPs on HEK 293 cells, which indicated lack of any noticeable toxicity of NPs.

FLG-PEG in spite of its persistance within liver and spleen tissue for 3 months, did not induce any noticeable toxicity or organ damage, and displayed significant changes in Raman spectra, indicative of their biodegradation potential.

The determination of chronic RfD values requires assessment of the No Observed Adverse Effect Level (NOAEL), which represents the highest continuous dose given to the most sensitive animal species that does not demonstrate any noticeable toxicity (Winter and Francis 1997).

Most intriguingly, 100% in vivo tumor elimination was achieved by intravenous injection of GO-PEG-DVDMS (2 mg/kg of DVDMS, 50 J) without tumor recurrence, loss of body weight or other noticeable toxicity.

Despite of long-term oral administration of RNPO, no noticeable toxicities were observed in major organs of mice.

In investigations where the toxicity of PPC has been examined in mice, oral administration at doses as high as 1.83 g/kg produce no noticeable toxic effects [ 6, 7].

Thus, these multivalent nucleic acid based structures with dual types of aptamers can be specifically applied as carriers of therapeutic nucleic acids without inducing noticeable systemic toxicity.

No noticeable tissue toxicity or abnormality was found in the corresponding tissue H&E staining images of all tested groups, which further guaranteed the in vivo safety of HRP RGD NPs for biomedical applications.

Also, agreeing with the in vitro studies that showed ignorable cytotoxic effect in the absence of caspase-3, the prodrug was effective only when combined with radiotherapy without any noticeable systemic toxicity in vivo.