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During the first six rounds, no noticeable affinity of the library to the target over background was detectable.
Neither the starting library nor the pools of the first six selection rounds showed any noticeable affinity to S1P.
SbAvd-1 was found to be cross-reactive with androgens highly similar to testosterone (DHEAS and androstenedione), and had noticeable affinity towards biotin.
BPA, which is described as an antiandrogen in vertebrates (Lee et al. 2003), also displays a noticeable affinity (IC50, 62.7 μM) for T. The difference in the affinity ratio BPA/T between Marisa (74, this study) and humans (4,720; Fang et al. 2003) is slightly less than that for the ER.
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The works of Locke and Newton manifest a noticeable intellectual affinity, and their endeavors have been seen as largely complementary, Locke supplying a detailed epistemology for Newton's natural philosophy.
It is noticeable that affinity of AmB for ergosterol is aproximatly 8.5 times more than that of cholesterol [ 30].
This difference in staining intensity became especially noticeable when TCR affinity was low.
The results showed noticeable differences in affinity for nuclear proteins between the two alleles.
This difference was most noticeable when the TCR pMHC affinity decreased, with a maximal effect observed with the 5Y ligand, where PKI treatment increased the MFI by almost 4·5-fold.
Despite differences in affinity, it was noticeable that all domains bound with a slow off rate.
It is also noticeable that chAb 18B7 had a higher overall equilibrium affinity constant (KA) than the parental mAb 18B7.
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