The SAS equivalent method was used to calculate the fiducial limits (confidence intervals), assuming normal function distribution and an "all or nothing" response parameter.
For ESCs, LIF concentration is converted into an all or nothing response [ 31].
This is in stark contrast to alternative regulatory elements such as transcription factors that produce an all or nothing response by directly activating or suppressing mRNA transcription.
Dubious as it is to equate every pirated copy of a game with a lost sale, it's likely that the virulent spread of cracked software on PSP played a part in killing off sales of all but the biggest brands or at least, scaring off publishers given to all-or-nothing responses in the face of copyright theft.
Dubious as it is to equate every pirated copy of a game with a lost sale, it's likely that the virulent spread of cracked software on PSP played a part in killing off sales of all but the biggest brands – or at least, scaring off publishers given to all-or-nothing responses in the face of copyright theft.
Because of such heterogeneity in protein abundance, population average measurements are not sufficient for investigating "all-or-nothing" responses; single-cell measurement techniques capable of capturing the dynamics of digital signal transduction are needed [ 12].
There is ample evidence to suggest that epigenetic perturbations are subtle and not all-or-nothing responses, resulting in shifts towards increased or decreased gene expression, a phenomenon that would be in line with the broad range of clinical manifestations reflecting a dynamic and individual response to alcohol exposure.
And yet Indians officials and Major League Baseball shrugged with a we-know-nothing response about Byrd's H.G.H. story.
Even as the president scrambled to blame the Clinton administration for the energy woes, House Democrats held a news conference today to upbraid Mr. Bush as having a "do-nothing response" because he is captive to the industry.
Sometimes the response is measured in terms of the proportion of individuals in a sample population that show a given all-or-nothing response (e.g., loss of reaction to a painful stimulus or appearance of convulsions) rather than as a continuously graded response; as such, the ED50 represents the dose that causes 50 percent of a sample population to respond.
