It's an offense that has shown noteworthy progressions — in yards per play, yards per game, and points per game, to name a few areas — compared to last season's unit, which held the team back in its 2014 losses to Georgia and Florida State.
It is noteworthy that during the progression of experimental periodontitis, high levels of IL-1 β and TNF- α have been positively related to RANKL expression [ 56, 57].
Despite the efficacy of TNF blockers for symptomatic control and improved quality of life in patients with AS, the lack of efficacy for radiographic progression is noteworthy.
However, the achievement of SD lasting more than 3 months in advanced cancer patients with previous disease progression is noteworthy, and in several cases has justified the further development of the agent under investigation.
As for potential implications in other key cellular processes that are deregulated during cancer progression, it is noteworthy that non-canonical Wnt signaling has also been demonstrated to play a crucial role in planar cell polarity and asymmetric cell division in stem cells (Bentzinger et al., 2014, 2013).
The results from this secondary analysis are particularly noteworthy: there was a significant progression to more advanced nodal disease in the nodal observation group, and there was a significant survival advantage (20%) for the SLN-positive patients who underwent immediate lymphadenectomy.
This is noteworthy, because retinopathy (sustained 3-step progression) was the primary outcome of DCCT.
It is noteworthy that invasive placentation and cancer progression share many features, like the invasive cell phenotype, vessel reorganization and neovascularization at the site of implantation.
It is noteworthy that while we assumed linear progression of cognitive impairment in clinical trials, future studies involving longer durations may require models of nonlinear profiles of progression of cognitive impairment.
Noteworthy, p53 inhibits both cell cycle progression and the mTOR pathway.,, - Rapalogs (rapamycin and its analogs), which not only inhibit mTOR but also slow down the cell cycle, partially substitute for p53.
When considering a clinical continuum between ALS and FTLD, it is noteworthy that so far no clear progression of minor cognitive or behavioral impairment to FTLD-ALS has been documented in longitudinal studies (55, 56).
