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Of note, meta-analysis of a two-study evidence base is not required in the moderate quality arm, where a conclusion would require both studies to have a statistically significant effect.
Note that meta does not add 1/2 to the number of events in calculation of the log-odds, and therefore calculates the standard statistic Q stand for the test of homogeneity.
With respect to precision, the GRADE guidance notes that meta-analyses of small trials can provide evidence of benefit with CIs that appear to convincingly exclude no effect; however, the results of reviews of such studies have often been subsequently refuted by larger trials.
It is interesting to note that meta-A genes and meta-B genes, also referred to meta-genes collectively, share three genes in common: DEK, DUSP1 and ITGA6.
Of note, our meta-analysis demonstrated the efficacy of non-pharmacological interventions for caregivers of schizophrenia, and supported the application in the clinical practice.
It is noted that meta-analysis studies of the existing data regarding spiral CT in acute PE have shown deficiencies in study designs, indicating that further research is required.
Of note, this meta-analysis gave no reference to 24-h sleep, which has only been estimated subjectively by epidemiological surveys at around 440 min in the general adult population [33].
Shearman and Pearson analyzed the portrayals of several of the series' regular characters as 1930s villains, noting several meta-references to the wider series.
Of note, a meta-analysis of CR therapies showed improvement in all-cause mortality only at 3-year follow-up and not earlier [ 42].
Of note, all meta-analyses that revealed statistically significant reductions in the rate of clinical heart failure related specifically to the use of anthracyclines.
It should also be noted a meta-analysis of nine trials revealed that relaxation produced less effect than psychological interventions on self-reported depression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com