Note the mismatches of side chain features here, as compared the nice match shown in Figure 4E,F.
Danilowitz notes the mismatch between the perpetual Jewish quest for safety, protection and acceptance, and Israel's stance on gay marriage.
It doesn't seem to me to be an open-and-shut case either way.UPDATE: Andrew Smithers has just come out with a new (alas, privately circulated) paper that bears both on this post and on yesterday's note about the mismatch between corporate profitability and business investment.
These two samples had sequences of 5′-GGATTAT TGT GAAATATTGA-3′ and 5′-GGATTAT GGT GAAATATTGA-3′, respectively, which were different from the target analyte aLF (sequence 5′-GGATTAT TGT TAAATATTGA-3′) only by a single base and two bases (note that the mismatch portion are highlighted).
Here it should be noted that the mismatch in years between ODA and outcomes (water and sanitation coverage, and IMR/CMR), though not ideal, does not negate the findings of this analysis.
Note that the mismatches are located at the 5'-end of the antisense strand, which makes this strand favorable for RISC loading [ 23].
While for some it was the lack of availability of funds per se that presented difficulty, others noted it was the mismatch between the availability of short-term funding for specific research initiatives and the requirements for longer-term investment in capacity that was the principle source of difficulties.
Actually, for the bassoon case, the amplitude variations over the time line of the note cause a mismatch with the window transform in certain frequency locations (i.e., blurred regions in the spectrogram).
Significant single marker associations with IgAD and/or CVID (p<0.01) were noted for SNPs in the mismatch repair complexes, MutSα, MutSβ, and MutSγ, the MRN complex, the extended RAD52 epistasis group, and AID.
It is also important to note that the amplitude of the mismatch is influenced by the absolute activation in the feature maps, as opposed to the relative activation resulting from the matching between matching template and item.
Taken together, this evidence may be consistent with the mismatch hypothesis noted above.
