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Notably, tissue stroma is preserved, allowing simultaneous labeling of other structures by immunohistochemistry or nuclear dyes.
Notably, tissue architecture of DPC-spheroids lowers Dkk-1 and enhances Wnt agonists' basal expression; probably contributing to DPC inductivity.
Notably, tissue engineering approaches are aiming to reconstruct the missing tissue using cell-based strategies in association with a biomaterial.
Notably, tissue from distant metastases showed even higher expression of Wnt than that from primary tumours (Supporting Information Fig S5C and D, left panel).
Notably, tissue immunostaining revealed that the receptor PlexinD1 is expressed in both endothelial and tumour cells (Supporting Information Fig 9D) consistent with the idea that Uncl-Sema3E could regulate both cell types.
Vascular endothelial growth factor (VEGF), perhaps the most critical regulator of angiogenesis in both tumours and normal tissue, is regulated by numerous factors, most notably tissue oxygen level (Shweiki et al, 1992).
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6 Synthesized predominantly in the ovaries in premenopausal women, the principal site of estrogen synthesis in older women and in men is in peripheral tissues, notably adipose tissue.
They did not report notably different tissue accumulations when the construct was administered i.v. or i.p.
Notably, glioma tissue homogenates were clearly distinguished from isolated primary glioma stemlike cell samples.
A significant number of other tumors, most notably soft tissue sarcomas, also form in this GEMM (44, 88).
Case definition for inclusion in the analysis required GAS to be cultured from sterile sites, notably operative tissue specimens +/- blood cultures.
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