They notably need to manage acute GI bleeding, a frequent and severe condition [1], the mortality of which has probably not changed for 20 years [1] but could be reduced through recent diagnostic and therapeutic advances [2].
They notably need to manage acute GI bleeding, a frequent and severe condition [ 1], the mortality of which has probably not changed for 20 years [ 1] but could be reduced through recent diagnostic and therapeutic advances [ 2].
Now the rest of Europe — and, notably, Germany — needs to make a choice to help Greece regain strong, sustainable growth by permanently addressing its financing needs.
Notably, Tup1 needs to be recruited to specific transcription factors by adaptor protein Suppressor of snf1 6 (Ssn6) and the homozygous ssn6 diploid S. cerevisiae fails to sporulate.
Most notably, it needs to be established whether or not Kjellman's view of this species matches the type specimen from Scotland [ 46].
The last part of the review addresses future challenges for multiple sequence alignment methods in the genomic era, most notably the need to cope with very large sequences, the need to integrate large amounts of experimental data, the need to accurately align non-coding and non-transcribed sequences and finally, the need to integrate many alternative methods and approaches.
But they share common ground on a variety of issues, notably the need for urgent action on climate change.
Rich economies with big trade surpluses and the ability to sustain budget deficits — most notably Germany — need to spend more, not less, at home and abroad.
This comes with its own set of challenges, however, most notably the need to ensure well-heeled customers a glamorous and indulgence-filled luxury experience in a destination mobbed by cruise ships.
If fundamental political questions – most notably the need for truly constitutional monarchy – were at the centre of debate in 2011, in 2012 it is economic governance that will dominate.
