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This chemical derivative of C has functional consequences for the cell, most notably in the control of gene expression.
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Some areas of the public sector, notably those in the control of the Scottish government, are seeing jobs of current staff protected from compulsory redundancy.
However, AC signaling is critically important in the development and function of cells and organs besides the central nervous system and is notably involved in the control of metabolic and cardiovascular processes.
Most notably genes involved in the control of cell growth and death and the immune system were identified, including members of the JNK pathway and PPARG.
Both enzymes are involved in the turnover of unincorporated or mistranslated mitochondrial translation products, notably in the quality control of several OXPHOS proteins [86].
Among these processes are the coordination of transport across the apical and basolateral membranes in epithelia, the locomotion of cells, the regulation of metabolic processes in the liver and, most notably, the control of cell proliferation and apoptosis [ 1– 3].
Most notably, we identified many genes involved in the control of cell growth and death and pathways involved in the immune system.
Notably, the control of blood glucose is similar in many respects: both humans and mice exhibit impaired glucose tolerance and overt diabetes that can be diagnosed with essentially the same symptoms and tests.
Notably, the PI3K/Akt signalling cascade plays a key role in the control of cell proliferation and survival [48].
Notably, p53, p63 and p73, have also been implicated in the control of cell differentiation (reviewed in 1, 3).
Notably small differences in recovery of bioluminescence (0.28 2.13% of pre-STZ bioluminescence levels) were associated with dramatic differences in the control of blood glucose.
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