April 18 , 1918Indore, India February 24 , 1998Pune, India Lalita Pawar, Indian actress whose career of more than 600 films was most notably defined by her roles as a mean, domineering mother-in-law; her performances were enhanced by a permanent squint in one eye, the result of an accident on a film set (b. April 18 , 1918 Indore, India--d. Feb. 24, 1998, Pune, India).
Until now, this drug-like space has been defined using cut-off values for permissible physical properties, perhaps most notably the values defined by the medicinal chemist Christopher Lipinski and his colleagues in the 'rule of five'2 (Box 1).
But for all of their similarities, Clemens and Pettitte are also defined by their differences, notably in the way they react to mistakes during a game.
Notably, little signal above the background defined by the Swiss mouse pooled sample was observed when serum samples from the Swiss8 and Swiss10 mice, which gave false positive results using immobilized 1, were incubated with the GAD65-GST-displaying beads.
Notably, ID may not only be defined by depleted iron stores (serum ferritin <100 ng/ml, absolute ID) [ 10], but also by limited mobilisation of iron from adequately filled stores (transferrin saturation [TSAT] <20%, and ferritin ≥100 ng/ml, functional iron deficiency [FID]) [ 10, 11]; particularly, if ferritin is upregulated by inflammation, which often occurs in tumour patients.
For years, the relationship has been defined by confrontation -- most notably over the summer, when Russia went to war with its Western-backed neighbor Georgia.
Professionally, she is relentless, sleeping at work and notably obsessed with detail in a police department defined by its failures.
Notably, we detected localized regions of increased substitution, defined by a clustered difference of three or more amino acids, in 10 genes.
Notably, the sub-boundary portions of each DMV defined by the original study often showed higher methylation levels than its central portion (Additional file 5).
Aggressive phenotype of metastatic cells is defined by the loss of epithelial characteristics42,69, notably E-cadherin involved in cell-cell adhesion70, and the increase in cell motility and expression of mesenchymal markers, such as vimentin71.
Some of the patients had only upper respiratory tract infections, notably sinusitis, whereas others had lung parenchyma abnormalities as defined by computed tomographic scan imaging.
