We notably assess the effect on the model predictions of uncertain values for some of the parameters that are difficult or time-consuming to measure (such as the protein or mRNA half-lives).
The respective technique provides thrust slip curves, which reflect tire size, loading, inflation pressure and tread pattern design, e.g. tread density, lug angle, pitch, height and tire casing lay-out and thus can be useful notably in assessing the traction properties of new tire designs.
The exact relationship between TIL of the primary cancer and peripheral NK cells activity should be further explored, notably in assessing the role of ADCC in the adjuvant setting in patients treated with cetuximab.
Given the inevitable constraints on funds available for all public sector interventions, economic evaluations are increasingly used as one key input to decisions on how to allocate resources to various health system actions, most notably for assessing pharmaceuticals, medical devices and procedures [ 25].
The objectives are to investigate features of HO for the first time in a large sample of patients and notably to assess if the time of surgery is associated with the risk of early recurrence of HO.
Notably, we assessed the question of cell death pathways (apoptosis, necrosis) evoked by these drugs in melanomas.
Notably, as assessed by average Ct values, in some cases (NSCLC- 81, ovariaNSCLC- 816), LAGE-1 mRNA was expressed at significantly higher levels than NY-ESovarian
This descriptive parameter has frequently been used to describe and analyse aspects of gait variability in humans [ 24], notably to assess the risk of falls in elderly people [ 25].
Notably, we assessed three N-terminal PD-associated PINK1 mutations located close to the cleavage site and, while these do not prevent PINK1 cleavage, they alter the ratio of full-length to ΔN-PINK1 protein in cells, resulting in an altered mitochondrial phenotype.
Notably, we assessed the influence of methotrexate and sulfasalazine, the most commonly used disease-modifying antirheumatic drugs (DMARDs) within our RA cohort; however, many other medications were used, which may be important if the drug has enzyme-modulating effects or causes a rise in ALT concentrations.
