The model resembles the ODE model in Cantone et al. (2009), but notably approximates the Hill-type kinetic rate laws by step functions.
Notably, they observed an approximate two-fold reduction in active CD36 protein at the plasma membrane, coupled with a similarly decreased level of nonesterified fatty acid (NEFA) released from VLDL by the left ventricle.
Notably, neither situation predicts the approximate two-fold asymmetry in Ds distribution across the cell axis that is experimentally observed (Brittle et al., 2012, see 'Discussion').
Notably, this quantification was only an approximate evaluation of the nonlinear concentration curves, but clearly demonstrated the feasibility of the HT-ChemoChip for generating large-scale 3D gradients of different steepness for high-throughput chemotactic assays.
When the results of both tools are merged in a union of events, recall and F-score are both notably higher in the stringent and approximate evaluations compared to individual tools and the precision is greater in the stringent evaluation.
Notably, survival curves of SHH tumors increasingly approximate with extended follow-up.
Notably, our calculated lifetimes of DOR homodimers approximate the association and dissociation kinetics of M1 muscarinic receptors assessed by single-molecule studies (12).
The adjusted value, say c ∗, is found empirically, in a simulation experiment using synthetic datasets; see DiCiccio and Efron (1996, notably sec. 7) for bootstrap methods for approximating confidence sets.
Notably, the dose of 100 µg Fe/ml approximates Fe concentrations in human plasma detected shortly after intravenous injection of clinically approved doses of nanoparticles such as MION [20].
Notably, DynaMine does not predict protein backbone dynamics directly, but approximates it using NMR order parameters.
As the OMSS configuration approximates the clinical situation, the torque loss is notably higher than in the in vitro activating experiments.
