Many of the subjects (with no notable sex difference) practised sporting activities (volleyball, soccer, swimming, dancing) once or twice a week to keep fit.
For benzidine and safrole, there was a notable sex difference, with high liver tumor incidence observed for early postnatal exposures of male, but not female, mice.
In the rat, not only is the elimination half-life of PFOA shorter than that in monkeys and humans, but a notable sex difference exists (Kemper 2003; Kudo et al. 2002; Vanden Heuval et al. 1991).
Of these 8 genes, CYP2C9 (rCYP2D61), CYP2D6 (rCyp2d4), and EGFR (epidermal growth factor receptor), exhibited notable sex-differences in gene expression patterns in this study.
Their role in the kidney, and particularly their notable sex-difference in expression, requires further investigation.
Primary headache disorders, including migraine, have notable gender differences in prevalence [7, 8], which are mainly rooted in differences in sex hormones, but women's social disadvantage may also play a role [9].
There were no notable ethnic or sex differences in the proportions completing the four measurements.
Expression profiles for specific examples of genes found in xenobiotic metabolism pathways (Cyp2c11, Cyp2e1, Cyp3a23/3a1, Gstm1, glutathione-s-transferase mu 1; solute8, solute carrier family 22 member 8) and energy metabolism (Phgdh, 3-phosphoglycerate dehydrogenase), which exhibit notable sex and age related differences, are shown in Figure 7.
