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Moreover, it displayed notable selectivity for ketamine ion over other species such as inorganic and organic cations and different excipients which may be present in pharmaceutical preparations.
In contrast, one small molecule generated by diversity-oriented synthesis showed notable selectivity for immortalized BJhTERT cells over the transformed BJELR derivative (Supporting Figure 8D,E).
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Regardless of the notable selectivity of the various indirubin analogues, they all share a common interaction pattern with their target enzyme active site (for example, see PDB structures 1E9H, 2BHE, 1UV5, and 1UNH).
The GQDs synthesized in this study are excellent sensing materials for trivalent iron cation with both notable selectivity and sensitivity.
Caspase-8 demonstrated notable selectivity among the caspase substrates, with highest catalytic activity for IETD-AMC.
The catalysts show suitable conversion of phenylacetylene and notable selectivity to styrene with 90%.
Emerging technologies such as pulsed electric fields (PEF) and ultrasound (US) treatment have been demonstrated to offer a notable potential and selectivity for extraction purposes.
Selectivity Selective for exogenous CEST agents.
The selected compounds differ in their selectivity for individual transporters.
Though the biological activities found were generally insignificant to poor, two compounds, one of which possesses a reasonable binding affinity for mGAT1, rac-57, the other a notable inhibitory potency at mGAT4, rac-84, both displaying a slight subtype selectivity for the individual transporters, could be identified.
Selectivity for EB was affected by temperature.
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