The selection of the criterion of path optimality, such as metabolic energy, length and time of traveling or a combination of these criteria, are another notable problem in this process [49].
The chief notable problem in designing the albumin- and chitosan-based nanocarrier is to attain formulation of small-sized (<50 nm) albumin nanocarrier core.
However, despite the success of Drude's free electron model, it had one notable problem, in that it was unable to correctly explain the electronic contribution to the specific heat of metals, as well as the temperature dependence of resistivity at low temperatures.
They tried running the ball through the middle, but this has been the most notable problem area: in the first three games, the Giants generated 82 yards on 38 attempts when running behind the two guards and the center.
However, a notable problem emerged in the current IR systems is that the input queries are usually too short and too ambiguous to express their actual idea which largely affects the performance of IR systems.
The most notable problem is the fact that the researchers destroyed datasets in order to preserve commercial confidentiality.
The most notable problem occurred at the speed-skating oval.
Muscular hypotonia is one of the most notable problems for general anesthesia because neuromuscular blocking agents (NMBAs) can have an unexpectedly prolonged effect in patients with hypotonia.
The most notable institutional problems in these countries have been related to the inflexibility of forestry institutions to change with evolving demands of society.
