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Tau is expressed throughout the adult human central nervous system and tau pathology, namely neurofibrillary tangles, is a notable pathological feature of a range of neurodegenerative disorders, including PSP, CBD (16) and AD (10).
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For example, Desouky et al. [ 45] reported extensive ultrastructural alterations to hepatopancreas epithelial cells, the most notable pathological features including vacuolation, degradation, and distinct cell lysis in red swamp crayfish following acute exposure with insecticide ethion (0.36 mg L−1).
However all of these mouse models had shortcomings, of which the most notable is failure to exhibit degeneration of the nigrostriatal system, a key pathological feature of PD (Manning-Bog & Langston 2007).
Protein aggregates are a common pathological feature of most neurodegenerative diseases (NDs).
Microhaemorrhages are a well-known pathological feature of schwannomas.
Lewy bodies are a key pathological feature of PD.
No pathological feature was detected.
No patients with depression presented notable pathological findings.
No notable pathological change was observed in those rats.
Pulmonary toxicity causes notable pathological effects such as fibrosis, inflammatory changes and degeneration of epithelial cells.
Apoptosis is a typical pathological feature of liver diseases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com