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The homage to Stanley Kubrick's "The Shining" in the opening is notable, too, for its irritation level.
"Women most often have vaginal irritation but a notable few have systemic flu-like symptoms, and a rare few have potentially deadly anaphylaxis," he said.
No skin irritation was noted.
The improvements in joint pain and physical stamina in the RYGB group were notable and may, together with improvements in skin irritation, water retention, foot problems, and shortness of breath, have resulted in easier performance of everyday personal hygiene, housekeeping, shopping and walking.
Transepidermal water loss (TEWL) was reported to predict the irritation potential of a given compound, e.g. a notable increase of TEWL, meaning a significant reduction of the skin barrier function, was recorded when sodium laurylsulfate (SLS) was applied on the skin [43].
It's a dependable source of surprise, puzzlement, irritation and delight, offering an eclectic mix of rising local talent, offbeat takes on popular culture and notable but not quite household-name artists from all over the world.
For me, it's a toss-up between Owen Wilson and Miranda July in the Bile-Inducing Irritation Stakes, but of course, one (wo)man's annoying is another's dreamboat, and I observe some notable omissions: floppy-haired fops Keanu Reaves and early Leonardo DiCraprio, for example, will always hold a space in my heart, no matter how irritating.
Irritation = suspicion.
Regularly monitor the irritation.
My irritation shocked me.
His demeanor radiated irritation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com