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Nevertheless, notable inhibitory effects of these four compounds on LTC-14 cell proliferation were observed (Fig. 3).
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PA from subcritical water extracts of S. senanensis leaves showed notable inhibitory effect on the histone demethylase JMJD2A.
Moreover, naviculan displayed a notable inhibitory effect on fusion between the cells that express CD4 receptor and HIV gp160-expressing HeLa cell line, which was used as a model system of HIV infection.
Moreover, endogenous and synthetic PPARγ agonists elicit notable growth inhibitory effects in vitro and in vivo (colon, breast and prostate carcinomas) and are capable of preventing metastasis [ 2, 5- 9].
We discovered that mutation of the RGD motif in human IGFBP-2 did not cause any notable changes in the growth inhibitory effects of IGFBP-2 in this animal model.
It is notable that the inhibitory effect of PGE2 on collagen and DNA synthesis was only significant at a concentration of 1 μM, whereas in lung fibroblasts effects have been observed at concentrations as low as 10 nM [ 41].
A notable feature of the NCI-60 screen is that the growth inhibitory effects of ML240 cluster in a narrow range, suggesting that specific genotypes do not greatly influence cellular sensitivity to this compound.
Inhibitory effects of SLE on melanoma cell migration and invasion.
Preimmune sera had no inhibitory effects (Supplementary Fig. S3).
Finally, we evaluated the inhibitory effects of crude cell lysates.
(D) Effects of STAT3C overexpression on SLE-mediated inhibitory effects on cell invasion.
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