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The intervention would still be likely to have a pronounced and negative net-monetary benefit resulting from notable incremental costs and very small incremental QALY.
The results of the present analysis indicate that, assuming overall vaccination coverage of 70%, the vaccination of both girls and boys using the quadrivalent HPV vaccine was associated with notable incremental clinical benefits versus a strategy of girls-only vaccination.
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Overall, innovation is incremental with some notable exceptions, such as, Tesla, and Local Motors.
But the more interesting figure in the firm's release of July 2012 data is not this incremental increase — although it's notable as an indication of just how fast the smartphone market is growing.
It is notable, however, that the observed benefit was incremental to all other traditional prevention methods (extra depth shoes and pressure-relieving molded insoles, podiatrist, neuropathy assessment, diabetes education, and vascular assessment).
Pragmatic, conciliatory, legalistic and incremental, he pushed what might be called, with a notable exception or two, an anti-Bush doctrine.
It was notable that different data bases and need for separate statistical methods produced estimated incremental costs that did not vary greatly.
After annealing at 600 °C the initial hydrogen concentration has decreased by ~90% with about the same incremental increase in the crystallite size as at 400 °C, and therefore a more notable decrease in E04 is expected.
This release is somewhat notable as it underscores Microsoft's faster release strategy for non-numbered releases, which is to say smaller, incremental updates rather than platform-wide releases.
Sensitivity analysis determined incremental costs to be insensitive to variation in most parameters, with only the treatment effect on weight having a notable impact on the incremental QALYs; however, there were no scenarios which raised the ICER above £15,000 per QALY.
This study represents a notable advance over most existing studies of protein evolution since it examines the wholesale repurposing of a protein rather than an incremental shift in activity or specificity.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com