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Breast cancer, prostate cancer, and positively-staining HNSCCs and ESCCs all exhibited notable elevations of both nuclear and cytoplasmic Ep-ICD compared to the normal tissues and prostate benign hyperplastic tissues analyzed.
Small elevations of one or more liver tests may occur in up to 15% of patients taking NSAIDs, and notable elevations of ALT or AST (approximately ≥3 times the upper limit of normal) have been reported in approximately 1% of patients in clinical trials of NSAIDs.
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As shown in Figure 4d, exposure of A549 cells to 8 μM SeC alone resulted in notable elevation of phosphorylated p53 and phosphorylated histone in a time-dependent manner.
Interestingly, such intensive clinical exacerbation was marked at the hyper-acute phase ranging from 6 h to 12 h after E5415A injection (Fig. 1b), which coincided with a notable elevation of the E5415A concentration in the blood (Additional file 3).
13 Notable elevations associated with shigellosis, 14 the enteric infection with the most pronounced impact on linear growth, 15 also supported its evaluation as a biomarker of intestinal permeability and protein wasting in the evaluation of environmental enteropathy.
These results are in agreement with Tunali-Akbay et al. [ 27] who demonstrated that rats treated with MTX exhibited a toxic effect on liver where it provoked a notable elevation in serum activities of ALT and AST.
These HRV effects include a notable elevation in rMSSD with O3CB accompanied by a delay in HR recovery.
Most notable is the elevations of C20 5 n-3 (EPA) as well as infusion of C22 6 n-3 (DHA).
Laboratory findings in both patients (Table) consisted of marked leukocytosis with notable eosinophilia and elevation of liver enzymes.
6. Elevations of ROS.
Also notable are a proposed elevation of farmer's rights, a more equitable system of land rights and a revamping of the antiquated household residential system, known as hukou, that made it nearly impossible for nearly 200 million migrant workers to transfer social welfare benefits from their hometowns to their places of employment.
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