Unlike the responses of the leaf, root tissue showed notable down-regulations, most related to protein phosphorylation and enzyme link receptor protein signaling pathway (Figure 3E).
The most notable down-regulation of molecular functions in affected tissues were the numerous GO terms related to kinase activity.
Other notable down-regulated gene ontologies include one gene corresponding to pinocytosis and endocytosis, and one gene related to natural killer cell mediated cytotoxicity.
The band 3 anion transport protein gene, the major glycoprotein of the erythrocyte membrane, also suffered a notable down-regulation in head kidney (FC = -6.6) and spleen (FC = -4.6).
The notable down-regulated genes in the colonic mucosa of mice treated with AOM/DSS were the peroxisome proliferator activated receptor binding protein (Pparbp, 0.06-fold decrease at wk 10) and the transforming growth factor, beta 3 (Tgfb3, 0.14-fold decrease at wk 10).
For its part, ExxonMobil has come some distance from its earlier period of funding climate-change skeptics; its new proposal is credible, and puts a notable foot down on one side of a carbon-policy debate that has yet to reach resolution, and which is likely to become fluid later this year.
In terms of name recognition, it's a notable step down from a Spotify, but when it comes to taking music and leaving the phone behind, it's a start at least.
The laptops promise seven hours of battery life (a notable step down from the former promise of 12 hours), coupled with quick charging, which should give users a full charge in 80 minutes.
If these teams both weren't in the middle of such lousy seasons, and if this game-ending play was to occur during a more satiable marquee lineup, it'd notable go down as one of the most amazing blocked field goals in history.
Notable put-downs heard outside my special-ed classroom included "dimwinky," "retardochuckles" and "the meat in the sandwich of stupid".
Other notable genes down-regulated by trypsin were cathepsin D (0.3 fold of control) and telomerase reverse transcriptase (0.5 fold of control), while protein phosphatase 2C was upregulated (3 fold) by PAR2 activating peptide.
