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TNF-a at this concentration is not wholly specific for MAdCAM-1, other adhesion molecules, e.g. VCAM-1 and ICAM-1 are also similarly mobilized by this concentration of TNF-a (data not shown), while the total cell protein is unaltered.
Similar(59)
However, incretins-induced CD36 and ACAT-1 downregulation was not wholly abolished by specific inhibitors of adenylate cyclase, PI3K, PKA, ERK (ESM Fig. 2) or PKC (data not shown).
The point is that these ancient TFs are broadly or ubiquitously expressed and are not wholly dedicated to the cardiac-specific functions.
The majority of funding has gone to organisations that are not wholly dedicated to women but are running specific projects aimed at their welfare.
Not wholly.
Not wholly uninteresting.
But not wholly unfair.
They were not wholly wrong.
It is not wholly convincing.
This is not wholly true.
He was not wholly wrong.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com