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However, this will yield more and more genome sequences that are not well assembled, and will hinder thorough annotation when no closely related reference genome is available.
Chicken chromosome 16, like the zebra finch, is not well assembled at this point so it is possible that these genes will be found as the chicken assembly continues to improve.
However, due to the shorter reads they produce compared with the traditional Sanger method, genome sequencing based on new technologies will yield more genome sequences that are not well assembled [ 2, 3], which in turn will hinder comprehensive annotation of the protein-coding landscape.
Four of these genomes (horse, chimpanzee, rhesus, and orangutan) are not well assembled: their draft genomes have nearly twice as many contigs as there are chromosomes but the effect on our adjacency-based distance estimator is minimal, given the large number of markers.
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It is highly likely that the organisation of the GiMAP loci is the same in the case of Acropora millepora; all of the A. millepora GiMAP transcripts map to a region of similar size to the A. digitifera locus, but this region of the genome is not sufficiently well assembled to unequivocally confirm the organisation shown.
Consistent with this, we found that FN1 matrix was not well-assembled in integrin α5-null embryos.
Without well assembled genome sequences, conventional whole genome comparison methods, such as whole genome alignments, might not be applicable.
Hesser described it as well assembled.
As a whole, the interior is rather plain and functional, well assembled from plastic materials of average quality -- though those who judge sports cars based on interior trim are probably not driving enough.
Many existing viral assemblers estimate local population diversity and are not well suited for assembling full-length quasi-species variants spanning the entire viral genome.
Therefore, repeat sequences are not well represented in the current assembled wheat genome.
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