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Thus, both citrullination of proteins and the HLA-DRB1* SE, are required for the development of arthritis: citrullinated fibrinogen but not unmodified fibrinogen could induce arthritis in transgenic mice carrying DRB1*04:01 (an HLADRB1*SE allele).

A pair of primers was designed to amplify the PHD3 promoter of both bisulfite modified methylated and unmethylated DNA but not unmodified DNA.

Thus, taken together these data demonstrate that N-α-Syn, but not unmodified α-Syn, has the capacity to induce specific immune responses by which exacerbates neuronal loss in the context of dopaminergic neurodegeneration.

More curious is why the entire cadherin-bound pool of β-catenin is not unmodified at S37 and T41, given that β-catenin becomes rapidly associated with a cadherin during biosynthesis [41].

Monoclonal antibody mAb4E12 recognized 2CA-modified, but not unmodified, PAD2 in western blots.

In addition, NX6/58α-β cells were activated by plate-bound Cy3-OVA, but not unmodified OVA.

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It is a customized Stanford Achievement Test, not an unmodified Iowa Test of Basic Skills.

Interestingly, the set of acetylated proteins (Figure 6A), but not the unmodified set (Figure 6B), showed also some conservation at the −3 to −7 positions.

Fluorescence microscopy showed strong binding of phage to the dye-modified beads (Fig. 4C), but not to unmodified control beads (Figure 4D) (p<10−36, t-test).

Not only unmodified, but also modified 35S promoters containing a 35S enhancer sequence were found to be highly methylated in the single copy transgenic gentian lines.

This antibody binds only to linker-coupled Biot derivatives but not to unmodified Biot that contains a carboxyl group.

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