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Therefore, tSNS treatment might be a valid option for the prophylactic treatment in patients who cannot take daily medications or in those experiencing a low migraine frequency and/or intensity when pharmacological preventive therapies may be not strictly indicated [10].
In their study, 22% of prescriptions by GPs were not strictly indicated on medical grounds.
Although NIV usage is not strictly indicated for agitated or uncooperative patients [ 3, 4], a questionnaire to pulmonologists and intensivists showed that 85%% of such patients had been sedated while under NIV, with 30%% receiving continuous sedation, suggesting its usefulness in clinical practice [ 5].
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Additionally, as adaptive evolution is likely to act on a small subset of amino acid residues and hence averages of substitution rates across the gene may not strictly indicate positive selection, HGGs were scanned for adaptive evolution using codon-based substitution models that allow ω to vary among sites, with the parameters of the model estimated using maximum likelihood.
We observed that the assumptions related to the distribution of errors and to constant coefficient of variation were not strictly established, nevertheless our simulations indicate that our model is robust regarding these assumptions.
The changed codon bias indicated that mutations were not strictly neutral [ 101, 110].
These results indicate that tracrRNA is not strictly required for NmeCas9 enzymatic activation, and expand the list of targeting activities of Cas9 endonucleases.
Predications indicating that something is not strictly speaking in the subject but nonetheless in it in some way can be of two sorts.
In any case, our results indicate that U2AF65/35 is not strictly required for splicing in vitro when PUF60 is present.
Collectively, these data may indicate that MeCP2 is not strictly involved in (global) transcriptional repression.
Indeed this very proceeding indicates that this requirement is not strictly applied.
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