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However, in many instances, these studies have not provided functional and mechanistic insight into the candidate genes identified.
It has also been limited to histological methods and has not provided functional data on susceptibility or defined its molecular basis.
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It is worth noting that this example is one for which all methods currently available as part of the Profunc meta-server for function prediction did not provide functional clues (data not shown).
These modalities do not provide functional information, however.
However, these studies do not provide functional evidence that activation of meningeal TRPA1 contributes to headache.
This simplistic approach focuses on gene discovery, which does not provide functional links between biological processes and traits.
One of the limitations of GWAS is that it does not provide functional information for associated genes.
We demonstrate the use of IsoCleft Finder with cases for which other methods did not provide functional clues.
While our experimental system clearly initiates VSG switching, it is not suited for completion of the process, most likely because it does not provide functional ESAGs.
Although structural neural networks do not provide functional connections directly, they have rich clues about how information processing is implemented in the brain.
However, we are aware of limitations of these tools and used comparative considerations and degree of conservation of amino acid residues do not provide functional evidence.
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