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However, the mechanism by which light regulates root development is not largely understood.
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The theory is largely understood.
The master must speak not only the language of the audience but also the ancient Kawi language spoken by the characters, which the audience largely understands as well.
The public largely understands that this is a problem; they largely accept the science.
Furthermore, the interface between the subunits is known to involve only the D1 and D3 domains (and not the D2 domain), but the precise details of this interaction are largely not understood, and remain one of the main enigmas in the complete understanding of pore formation for this class of toxins.
This transition, which is important in operation of nanofiber filters, is largely not understood.
The pathological consequences of AdoHcy accumulation as well as the molecular mechanisms triggered by elevated AdoHcy levels are largely not understood.
Their emissions from sources of combustion, man-made or through natural events, can modify the weather inadvertently by increasing the number of small water droplets while decreasing the production of rain or snow, an event that is still largely not understood yet generally accepted as an important factor in changing precipitation patterns [ 3, 4].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com