Although the Norman invasion caused some damage as soldiers looted the countryside and land was confiscated for castle building, the English economy was not greatly effected.
Adjusting for risk factors did not greatly change effect estimates of 3- and 7-day mean BS in the Renfrew Paisley cohort, but reduced those of the 31-day mean.
Removal of these 12 did not greatly change the effect estimates (table 4).
Similarly, pharmacological inactivation of PARP-1 during the post-incubation of C-1305-treated C-1305-treated C-1305-treatedncrease the effect of the TOPO II inhibitor (Fig. 4A, right panel).
In the same article (Schwartz et al. 2003), we also showed that the effects of PM10 on hospital admissions for all other cardiovascular causes are not greatly different from the effects on MI admissions.
"To be sure, requiring dancers to wear pasties and G-strings may not greatly reduce these secondary effects," Justice Sandra Day O'Connor conceded in her opinion for a plurality of four justices.
The TREM1, C-A-C (rs1817537-rs3804277-rs4711668), haplotype association appears to be driven by the effects of haplotype C-A (rs1817537-rs3804277), as the baseline was G-G-C and rs4711668 C was common to both the associated haplotype and the baseline, suggesting that this marker is not greatly contributing to the haplotype effect.
Thus, methylation at a single position (C13) in DNA 10 substantially diminished binding of Fe(II)·BLM A5, and this effect was not greatly enhanced by the introduction of additional methylation at C53 (Table 2).
A linear relationship has been observed between fitness cost and fraction of aggregated proteins (Geiler-Samerotte et al. 2011); such an effect would not greatly change the model discussed earlier, as it still results in a linear relationship between fraction of folded protein and fitness, albeit with a different slope.
A careful balance needs to be struck: for example, between the detailed modeling required to incorporate seasonal effects, which is crucial for some organisms, while recognizing that such effects are not greatly relevant for many others.
