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However, NSAIDs are not always sufficiently effective [ 1] and concerns about side effects result in a large unmet need in the treatment of canine DJD-associated pain.
Allopurinol may induce unacceptable side effects, and in patients with dose-limiting renal failure it may not be sufficiently effective.
In 2012, EU auditors ruled that European aid had not been "sufficiently effective".
"However, the recent detachment between central rates and Libor, on which most business borrowing is set, suggests an immediate cut in the central rate alone will not be sufficiently effective".
However, economic incentives may not be sufficiently effective in an urban context and among better-off people (Sun et al. 2011; Sun 2012).
Several cases have used visual BF up until now during balance training; however, this training method has not been sufficiently effective and could also reinforce visual reliance.
However, the general method of learning from examples in problem solving may not be sufficiently effective in problem posing because cognitive skills in problem solving and problem posing are different.
Although learning by solving examples is adopted in general education, it may not be sufficiently effective in fostering learner problem posing because cognitive skills differ between problem solving and problem posing.
Although RASVs have been successfully used to express recombinant antigens and induce protective immunity in animals [19], recombinant attenuated S. Typhi vaccines (RASTyV; vaccine strains synthesizing heterologous antigens) have not been sufficiently effective in human studies to justify commercial development [20].
In addition, small volumes might not be sufficiently effective.
Communication between the partners within the ECU has not been sufficiently effective.
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