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The cause of PD is not currently fully understood; however, the etiology of sporadic PD, the most prevalent form of the disease, is probably multifactorial, involving a combination of genetic, environmental, and unknown factors.
Whether different subpopulations of monocytes give rise to specific types of tissue macrophages is not currently fully understood, but there is agreement that the presence of the fractalkine receptor CX3CR1 marks inflammatory monocytes that migrate into tissues in response to its ligand [8,9].
More likely, the emergence of an epidemic or pandemic 'phenotype' is the result of epistatic interactions between sites within [ 17] or across segments, forming a constellation or network of epistatic interactions that are changing over time in ways that we do not currently fully understand.
While we do not currently fully understand how each individual transcript relates to protein expression, and how this may change with spatio-temporal context, the heterogeneity of the levels of transcript type among cell populations suggests that the 3′UTR may be important for fine-tuning MeCP2 protein expression to meet the homeostatic needs of individual microenvironments in the brain.
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Moreover, many disorders of the brain have a complex genetic underpinning, and thus it is not currently possible to fully recapitulate the complex genetic landscape in traditional animal models.
c P < 0.05, fully retired vs. not currently active d P < 0.01, fully retired vs. not currently active e P < 0.001, fully retired vs. not currently active Nearly a quarter (23.7%) of the fully retired respondents had explored becoming active in medicine again; respondents who were not currently active were twice as likely (50.3%) to report having explored returning to medicine (Table 5).
"However, Google does not currently have access to fully crawl the content on some sites, so it's not possible for us to surface all that information.
The Securities and Exchange Commission does not currently have the ability to fully monitor what, by most accounts, makes up a majority of the stock trading activity in the United States, according to former SEC lawyers.
However, my reading of the manuscript leads me to conclude that the authors do not currently have sufficient evidence to fully support either of these claims.
a P < 0.001, fully retired vs. not currently active b positive responses; multiple response permitted c P < 0.05, fully retired vs. not currently active Additional analyses were performed to examine possible gender differences in family and work responsibilities of our respondents.
The most frequently cited reason for being fully retired or not currently active in medicine was personal health issues (37.8% for both groups); this reason was frequently cited among those who had reentered active medicine as well (28.8%), second only to the need to care for young children (29.6%).
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