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Unlike other mitochondrial proteins, the N-terminal signal sequence of 3βHSD2 is not cleaved upon mitochondrial import.
However, TBC5180 was also hydrolyzed by ACE, whereas TBC5182 was not cleaved, suggesting that TBC5182 was a selective for ACE2.
However, in the presence of MTase, the specific recognition sequence in the dye-labeled DNA probe is methylated and not cleaved by restriction endonuclease.
The expansion of its use to a variety of further medical conditions associated with hypersecretion components is prevented partly because the involved SNARE isoforms are not cleaved.
These results strongly suggested that PRENCSO in the tissues of #6 and #10 bulbs was not cleaved by the alliinase, and that the alliinase activity may be significantly reduced.
All other tested DKPs were not cleaved by both strains.
In contrast, phenylalanine and methionine, which display little 15N-enrichment, are metabolized to tyrosine and S-adenosylmethionine, respectively, during which the α-carbon-nitrogen bond is not cleaved.
Similarly, endogenous MKK7 was not cleaved in human 293FT cells.
Ub-AMC was not cleaved by buffer alone or GST-FBXO2 (Figure 3E).
Signal anchors are found in proteins that are inserted but not cleaved in the ER.
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A further interesting observation is that the signal peptide of US2 is not cleaved off after translocation into the ER.
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