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Indeed, when AEN (Fig. 6B) or IL-6 [11] transcripts are overexpressed in the presence of SOX, they do not become sensitive to shutoff.
However, cells did not become sensitive to tamoxifen after IPA-3 treatment.
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An attractive aspect of the HSVtk/GCV enzyme/prodrug system is that this therapy benefits from the phenomenon known as "bystander effect", whereby even cancer cells that do not express HSVtk become sensitive to GCV due to the activation of GCV in neighboring transfected cancer cells.
This phenotype does not become less sensitive to LPS; that is, it does not become LPS tolerant.
However, the receptor does not appear to be directly responsible for drug sensitivity per se as different cell lines transfected with FBP cDNA did not become more sensitive to the drug.
The observation that H3-L61I and H3-L61V mutants do not show a temperature sensitive phenotype at 37° might indicate that although the structural rigidity imparted by isoleucine and valine at position 61 of histone H3 interferes with Spt16−interactions, it does not cause cells to become sensitive to elevated temperatures.
In addition to distancing, romantic partners who are not getting their needs met might become sensitive to their low return on investment.
When auditory fear conditioning was carried out with the low-intensity US, the formation of LTM but not STM became sensitive to striatal neuron ablation.
Suddenly, things that did not seem all that unusual a few weeks ago have become sensitive".
his eyes become sensitive.
When you step outside that space, things can become sensitive".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com