Exact(6)
The union's Scottish secretary Pat Rafferty said: "We are very disappointed matters could not be progressed particularly as we presented a number of proposals in a bid to resolve this dispute and we were prepared to work throughout the night if need be.
This exercise will not be progressed to unstable surfaces to ensure that similar neuromuscular effects are not seen in this group.
In light of well publicised withdrawals of compounds from the US market, 1 drugs with high risk of QT prolongation in such assays may simply not be progressed into human trials.
If this is determined intra-operatively, patients will not be progressed further into the study; 5) Medical/Anaesthetic contraindications to surgery; 6) Unable to comply with rehabilitation or attend follow up appointments as determined at the time of surgery (e.g. resides internationally); 7) Are currently pregnant.
High-throughput screens for multiple targets provide large amounts of data, and novel means are needed for turning this into meaningful information to support flagging-up of potential negative side effects that warrant further investigation in subsequent studies, or indeed to identify drug candidates that should not be progressed further.
In a compound development setting, the results shown in Figure 3 B and Figure 4 D suggest a strategy: a compound in which the simulated APD90 at any realistic EFTPC is markedly prolonged will have a strong TdP risk and should not be progressed to the market (unless the clinical benefit outweighs the safety risk, e.g. it is intended to be used as an anti-arrhythmic or an anti-cancer drug).
Similar(54)
Some fans left with half an hour remaining once it became blindingly obvious that their team would not be progressing.
But Gecko may not be progressing as quickly as Skype needs it to.
As a result, the case was "not being progressed" and had effectively come to a halt.
Tapit, the winner of the Grade I Wood Memorial, has not been progressing to the satisfaction of his trainer, Michael Dickinson.
However, we should point out that such policies have not been progressing well and have not achieved sufficient outcomes to date (Forestry Agency of Japan 2016).
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