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Thirty metabolites were quantified and four metabolites were semiquantified because calibration standards were not available (Supplementary Table S3).
Two siRNA sequences were used for any gene that had pre-validated siRNAs, whereas three siRNA sequences were used for genes for which two pre-validated siRNAs were not available (Supplementary Table 5).
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Although the full dataset from that study is not available, a supplementary table listing mRNA with significantly different levels between species does not contain transcripts encoding ligase IV or XRCC4.
In this survey, medicine prices from the Drug Prices Guide in 2011 issued by Management Science for Health (MSH) were adopted as the IRPs for core medicines, but because MSH prices were not available for most supplementary medicines, Spanish manufacturers' selling prices were used as their reference prices (supplied by WHO/HAI project member Carmen Peres-Carmen.
Where Cochrane data were not available we performed a supplementary search for placebo-controlled trials.
In these two studies adult proxy reports were not available to provide a supplementary perspective in addition to self-reports.
We next analysed exome data at PPP2R5B, PPP2R5C and PPP2R5D in a separate series of 152 individuals with overgrowth phenotypes for whom parental DNA is not available (the singleton series; Supplementary Material, Table S1).
In particular, STITCH provided a relatively extensive list of additional target annotations for many of the compounds, not available from the other resources (supplementary material Fig. S9).
Measurements of MUAC, BMI and especially suPAR were not available for all patients (see online Supplementary data file 1).
A further query restricted to these cohorts show the exact genome-wide genotyping arrays these samples have been measured on, and whether or not genome-wide imputed genotypes are available (Supplementary Figure S2).
When supplementary fodder is not available, bison may increase browsing (Kowalczyk and others 2011), but most often migrate to agriculture areas, where they stay till spring, as observed in Knyszyn and some parts of Białowieża Forest.
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