Telotristat etiprate, a tryptophan hydroxylase inhibitor, was previously evaluated in a Phase II randomized, placebo-controlled clinical trial in patients with carcinoid syndrome (CS) and diarrhea not adequately controlled by octreotide.
"Plum Island officials have not adequately controlled access to the pathogens," it said.
NPOIU operations were not adequately controlled in this regard," O'Connor wrote.
In addition, studies had not adequately controlled for MVT rates in adjoining communities (spatially autocorrelated rates).
When symptoms are not adequately controlled with one bronchodilator, addition of another bronchodilator is recommended.
If not adequately controlled, the self-induced tensile stresses may induce cracking of concrete at early ages.
Upper airway diseases are extremely common, and a significant proportion of patients are not adequately controlled by contemporary treatment algorithms.
In all cases, the FDR was not adequately controlled, although the difference between intended and actual FDR was notably smaller with MedianCD and SVCD normalization.
These pathogens pose challenges to growers because the diseases they cause are not adequately controlled by fungicides, rotation or, for many hosts, natural genetic resistance.
In regulatory trials designed to show a difference, newly diagnosed patients are randomised to a high versus a low dose of the investigational drug, and exit criteria are again predetermined for patients whose seizures are not adequately controlled.
Despite multiple available effective therapies for hypertension, many patients with high blood pressure in the United States are not adequately controlled.
