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Disruption of the co-repressor RIP140 in mice results in increased expression of genes involved in energy dissipation in white adipose tissue and cultured fat cells, suggesting that RIP140 is normally promoting energy conservation.
These data are consistent with the core pathway normally promoting endocytosis of E-cad from vertical junctions via asymmetric recruitment of RhoGEF2.
They are key sensors for a number of infectious agents, some of which are oncogenic, and they launch an immune response against them, normally promoting their eradication.
Importantly, simultaneous knockdown of faf and dor causes more extensive accumulation of Fmi in intracellular vesicles than knockdown of dor alone (Fig. 5L,M), consistent with a failure of Fmi deubiquitylation normally promoting lysosomal degradation of Fmi.
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For instance, the inclusion of the fibronectin EDII exon, normally promoted by the SRp40 protein, is inhibited when transcription is initiated at a promoter containing a binding site for the PPARγ transcription factor.
Another potential promoter of hybrid formation is RecA, the bacterial strand exchange protein that normally promotes the invasion of single-stranded DNA into duplex DNA to repair DNA damage.
And companies that normally promote their greenness are keeping an uncharacteristically low profile on their use of CO2.
Its draw is not one that communities normally promote: a climate that, for nearly half of the year, is exceptionally cold and exceptionally snowy.
Billboards in southern Nicosia, which normally promote the latest cell-phones, feature the word Ochi (Greek for no) against a depressing dark background.
HONEST TEA, like other organic beverage sellers, normally promotes its real leaves, fair trade certified tea, less sugary taste and environmentally friendly packaging.
But when the latest M.R.I. showed no significant improvement, doctors wondered if perhaps the boot was restricting blood circulation that might normally promote healing in the joint.
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