Sentence examples for normally maintained in from inspiring English sources

NLRP3 proteins are normally maintained in an auto-suppressive state, but upon activation by diverse stimuli, NLRP3 proteins bind to the ASC adaptor via a homotypic PYD interaction and ASC recruits pro-caspase-1 to initiate IL-1β processing and release.

Cells were normally maintained in DMEM or RPMI supplemented with 10% FCS and antibiotics (100 units/ml penicillin plus 100 µg/ml streptomycin).

CHO hERG cells were normally maintained in culture at 37°C.

pCLU1 carried terminal-protein (TP) at both ends and were normally maintained in the cytoplasm with the helper pGKL2.

Some glioma cells are derived from neural stem cells that are normally maintained in neurogenic niches in the brain.

PAX6 expression is normally maintained in proliferating cells of the anterior lens epithelium, and it is down-regulated in posterior lens fibres to enable terminal differentiation [ 25- 28].

In human thyroid cancer BCPAP cells harboring homozygous BRAF V600E mutation, BRAF V600E inhibitor, PLX4032, and MEK inhibitor, AZD6244, increased histone acetylation of the NIS promoter, suggesting that BRAF V600E normally maintained histone in a deacetylated state at the NIS promoter.

Since p53 is an important regulator of various cellular processes (including apoptosis), it has a short life-time and is normally maintained at low levels in unstressed mammalian cells via continuous ubiquitination and subsequent proteasomal degradation.

Thus, the NADP+/NADPH ratio is normally maintained at a low value in both cytosolic and mitochondrial fractions [ 50].

Having a short half-life, p53 is normally maintained at a low level in unstressed mammalian cells by continuous ubiquitination and subsequent 26S proteasome-mediated degradation.

The amount of free ferrous iron is normally maintained at a very low level in humans.