Your English writing platform
Discover LudwigExact(2)
Importantly, genotype also has a large main effect for these normalized traits.
Pooling together F3 families that share same fruit flesh color and thus the same CmOr allelic variation, normalized traits unrelated to CmOr allelic variation.
Similar(58)
The data is available on GeneNetwork [ 57] as strain means of each min-max normalized trait.
In the method of Zuk et al. (2012) products of normalized trait values are regressed against relatedness values.
First, we use the method of Zuk et al. (2012) in which products of normalized trait values are regressed against relatedness values obtained from detected IBD segments.
This transformation was used to generate inverse-normalized traits having a mean of 0 and a standard deviation of 1 which was then used in the regression analyses.
As another example of genetic architecture changing as different summary statistics are mapped, we find that QTL for optical density and body length largely overlap (as expected, given their tight correlation), but new QTL emerge when we map a normalized optical density trait (the optical density of each animal divided by its length, Figure 4).
Mean normalized values for phenotypic traits in the field.
We characterized the extent of pleiotropy within each five-trait matrix as the squared maximum contribution of any trait to the normalized m max, a metric that ranges from 1.0 (no pleiotropy) to 0.2 (all five traits shared mutational covariance to the same extent).
We did not observe a relationship between the magnitude of a mutation's effect on a trait (characterized by the trait's mutational effect kurtosis: Figure 4A) and the pleiotropic variance in that trait (characterized by the loading of the trait on the normalized pleiotropy eigenvector m max) (r = −0.028, d.f. = 3385, P = 0.105).
As a preprocessing step, the traits were quantile-normalized to have standard normal distribution.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com