Moreover, the identification of appropriate control genes presents a circular problem, because in order to find suitable genes for normalization, prior knowledge of their stable gene expression is needed, which also relies on properly normalized data.
To our knowledge, normalization of renal function under AZA was reported only in one case [ 12].
To our knowledge, normalization of inferior parietal activation with MPH has only recently been observed in ADHD patients, in the context of sustained attention (26) and interference inhibition (54).
There is no direct solid knowledge that normalization of plasma glutamine is associated with a better outcome; more than that we know that in the combined group of patients with a normal and/or a normalized plasma glutamine concentration there is a better outcome.
Egas also facilitates concept normalization by integrating and indexing a complete set of knowledge bases, offering heterogenous information targeting different domains of interest.
The Normalization of Bad Behavior There's solid psychology behind the normalization-of-bad-behavior phenomenon.
The incompleteness of annotation libraries poses a serious limitation to using this powerful technology since accurate normalization of RNA-Seq data critically requires knowledge of expressed transcript sequences [ 5- 8].
A comprehensive set of knowledge bases are integrated and indexed to provide straightforward concept normalization features.
Are they instances of knowledge?
