Sentence examples for normal sensitization from inspiring English sources

Although NMDAR function was disrupted in virtually all DA neurons in our NR1DATCre transgenic mice, these animals demonstrated normal sensitization to repeated cocaine treatments in both, the home cage and a novel environment.

Inhibition of IGF1 signaling was required for starvation-mediated protection of normal cells and sensitization of cancer cells to therapeutic drugs [ 22, 23].

We showed that human Abs that are specific for the CDR2-encompassed Met 55-cored region could be regularly generated in vitro from normal donors after sensitization with a heterotopic peptide.

It is thought that this conditioning may be a major factor in relapses that occur in patients months to years after they stop smoking an extremely stressful situation and nicotine receptors that have returned to their normal state of sensitization may be enough for the patient to start smoking again.

Thus, our study reveals that in addition to the inhibition of proliferation-enhancing IGF1 signaling pathway, the activation of the AMPK signaling cascade, which suppresses proliferation, is also involved in the starvation-induced protection of normal cells and sensitization of cancer cells to CDDP treatment.

The normal progression of cocaine sensitization in NR1 KO mice in this, and in previous studies was generally unexpected because it was thought that NMDARs on VTA DA neurons were necessary to support this response.

Although some eosinophils reside in normal guinea pig lungs, sensitization without antigen challenge is sufficient to recruit additional eosinophils to the lungs (Adamko et al. 1999).

It was therefore hypothesized that a continuous supply of P. acnes-sensitized T cells should lead to chronic pulmonary granuloma formation, and consequently, we performed continuous remote sensitization of normal mice with P. acnes.

This study is designed to confirm the No-Observed-Effect-Level for induction of dermal sensitization in a normal human population.

Fluorescence microscopy showed maximum levels of mTHPC in normal pancreas 2-4 dafterfter sensitization and in tumour at 4-5 days.

However, given that survival and death pathways are shared by normal and tumor cells, differential sensitization of tumor cells without affecting normal cells has been the goal to avoid the issue of toxicity to normal tissue.