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In most fz or dsh1 mutant SOPs, the cell division plane is perpendicular to the crescent, thereby leading to normal segregation of Numb and Pon.
In this context, initial analyses revealed a normal segregation of these lineages in Coro-1A−/− animals but a reduced density of peripheral T lymphocytes, in general agreement with published data on coronin-1A knockout mice [21], [23].
EE precociously increases Brain Derived Neurotrophic Factor (BDNF) in the retina, in parallel with the precocious segregation of RGC dendrites; in addition, EE counteracts retinal BDNF reduction in DR retinas and promotes a normal segregation of RGC dendrites.
With comprehensive screening of both polar bodies, cases in which there are isolated reciprocal aneuploidies with normal segregation of all other chromosomes in maternal meiosis have an opportunity to produce a euploid embryo.
Proteolytic mechanisms exist to clear excess cenH3 from chromosome arms in both yeast and Drosophila, resulting in normal segregation of chromosomes (Collins et al. 2004; Moreno-Moreno et al. 2006).
Alleles of different copy number, while clearly inherited in a Mendelian manner, combine to give a diploid copy number genotype which can vary substantially between parent and child, and between siblings, due to normal segregation of homologous chromosomes.
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There were 42 oocytes from 40 individual patients in which the two polar bodies had isolated reciprocal abnormalities, that is normal segregation patterns of all autosomes with the exception of one or two chromosomes that had a loss in one polar body followed by its gain in the second polar body or vice versa.
However, eight regions showing normal segregation in the F2 showed overabundance of the S. bicolor allele in the F5 RILs.
These markers were usually included in segregation data set for genetic map construction from F1 progeny, with the hypothesis of equal recombination rate and normal segregation between male and female genomes.
Strain cen1:: R-arg3 + displayed a slight increase in the fraction of cells with mitotic defects (77% normal segregation, N = 70), despite having no observable phenotype on media containing TBZ or Phloxin B and normal cell morphology.
This result indicates that normal segregation is required for normal SeqA focus formation.
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