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The single insert control strain cen1:: L-ura4 + segregated similarly to the wild-type strain (92% normal segregation, N = 61).
To determine whether there is a critical period for development of eye-specific layers in the lateral geniculate nucleus (LGN), we prevented the normal segregation of retinogeniculate afferents and then allowed an extended period of time for recovery.
Note that the normal segregation is also slightly reduced by the modulation when the optimal period is used.
This result indicates that normal segregation is required for normal SeqA focus formation.
In most fz or dsh1 mutant SOPs, the cell division plane is perpendicular to the crescent, thereby leading to normal segregation of Numb and Pon.
In this context, initial analyses revealed a normal segregation of these lineages in Coro-1A−/− animals but a reduced density of peripheral T lymphocytes, in general agreement with published data on coronin-1A knockout mice [21], [23].
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Mechanisms causing the asymmetric wall-normal segregation were explored with the focus on the moving-wall region, where the quasi-coherent turbulent structures were absent, and the local fluid structures were dominated by imprints of the LSSs.
Thus, nut2 is required for normal chromosome segregation and its deficiency rescues chromosome segregation when condensin is impaired by the cut3-477 mutation.
Although deletion of spo0J (parB) of B. subtilis leads to a considerable increase of anucleate cells during vegetative growth, the rest of the cells still exhibit a normal chromosome segregation pattern [ 27]; moreover, deletion of soj (parA) has no significant effect on chromosome segregation [ 46].
Interpretation of such studies is hindered by the limited knowledge of normal functional segregation.
Daniel Barbash, Molecular Biology and Genetics, is determining the identity and mechanism whereby one type of selfish DNA, called meiotic drivers, are able to distort normal chromosome segregation into eggs.
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